The Danger Zone:
Well it's a non-shave entry again. And since I have been all about my genes lately...here is one that I really found VERY interesting! One of my gene expressions is:
ACTN3 - rs1815739(C;T)
From the report...
"Alpha-actinin-3 is a protein that plays a role in the contraction of fast-twitch skeletal muscle fibers and is encoded for by the ACTN3 gene. This polymorphism, rs1815739 (also known as R577X), is located in the ACTN3 gene. The variant allele, T (sometimes called X), has been reported to introduce a premature stop codon into the gene which prevents the ACTN3 protein from being produced. This polymorphism is common in the general population, with approximately 20% of individuals worldwide having two copies of the variant allele. Individuals with the (T;T) genotype are deficient in α-actinin-3, however, rather than causing muscle disease, this deficiency appears to alter how muscles function. Sprinting and power activities require fast-twitch muscle fibers, which do not function optimally without α-actinin-3. However, muscle fibers without α-actinin-3 appear to be resistant to fatigue and thus may be beneficial for endurance activities. This genotype, rs1815739(C;T), may be associated with intermediate fast-twitch muscle performance."
The report goes on to link studies that support and define this expression and suggests that people with the C;T expression may benefit from High-Load Low-Repetition resistance training to build muscle and may benefit from High Intensity Training (HIT) to improve VO2 Max (maximal oxygen uptake - basically, aerobic endurance) during endurance exercise.
At any rate...this is one of the more interesting items on the report that I think I may be able to use. But like all things...this may not be set in stone and I just need to do some experimentation!
Hope the cadre is having a wonderful weekend!